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Pythiomics API 

Seamless Queries. Seamless Computation. 

Get programmatic access to Pythiomics — our trusted, well-curated multi-omics database — directly from your native environment.

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Access, Query, and Compute with Confidence

The Pythiomics API is a software package that provides programmatic access to Pythiomics, our well-curated and standardized multi-omics database of more than 10,000 datasets. It enables retrieving and quering the database directly from native bioinformatics environments such as Jupyter Notebook and RStudio - and receiving results in various formats, including text-based matrix files, XML, or JSON.

Programmatically Explore
10,000+ Multi-omics Datasets

Explore a standardized and reliable data source of comprehensive multi-omics data meticulously curated, harmonized and QC'ed.

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Bulk RNA

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Visium HD & Xenium

Coming soon

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Single-cell RNA

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Metabolomics

Coming soon

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Proteomics

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ATAC-Seq & CITE-Seq

Coming soon

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Visium Spatial

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CHIP-Seq

Coming soon

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CosMx

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Mutation & GWAS

Coming soon

Tailor-made for Computational Biologists and Bioinformaticians 

Whether you're building custom workflows or running large-scale analyses, Pythiomics API puts trusted omics data at your fingertips — ready to explore, compute, and publish.

Programmatic Access

Integrate directly with your codebase using Python or R.

Trusted Data

Work with harmonized, quality-controlled omics data curated by experts.

Flexible Integration

Use within familiar tools like Jupyter, RStudio, or your custom pipelines.

Scalable Analysis

Build and run scalable workflows using clean, structured omics data.

Flexible Access. Flexible Analytics.

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Retrieve expression profiles across cell types, tissues and conditions

Explore expression patterns and proportions across our Pythiomics database. 

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Summarize important DE genes and proteins across cell types, diseases, or treatments

Find differentially expressed genes across conditions, tissues, or treatments across datasets and summarize findings. 

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Take a deep dive into individual datasets

Download and perform in-depth analyses into a dataset of interest. 

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Share and collaborate

Upload and share results with bench colleagues through C-DIAM GUI. 

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Pythiomics API request form

Start making discoveries, today.

Request a trial of Pythiomics API
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